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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 12.12
Human Site: S1383 Identified Species: 20.51
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 S1383 I I G S S S A S H T S Q A T S
Chimpanzee Pan troglodytes XP_510594 1417 158822 S1383 I I G S S S A S H T C Q A T S
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 S1382 I I G S S S A S H T S Q V T S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 S1382 V T G S R S A S C A S Q A T S
Rat Rattus norvegicus Q6AYJ1 621 69624 R592 A V T M Q V K R S T Q S S V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186 T762 S T S D G F Q T A A G S G R K
Chicken Gallus gallus Q9I920 1142 126164 A1113 A A P A Q S S A L R G A G A R
Frog Xenopus laevis Q9DEY9 1364 152305 K1335 S S Y I S G S K T G A D K R P
Zebra Danio Brachydanio rerio XP_701357 1261 139417 E1232 M V K K C L G E L N D L C K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 A1454 G R G G R A G A K R A E S S A
Honey Bee Apis mellifera XP_396209 961 109321 K932 A T V S T V T K K I D K I L V
Nematode Worm Caenorhab. elegans O18017 988 110641 A959 T K K P R A T A P S A R G K T
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 D1358 A P N P K D V D G M E D E T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 P1409 Q I R Q S Q L P K N T T S S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 93.3 93.3 N.A. N.A. 66.6 6.6 N.A. 0 6.6 6.6 0 N.A. 6.6 6.6 0 13.3
P-Site Similarity: 100 93.3 93.3 N.A. N.A. 73.3 20 N.A. 6.6 26.6 20 13.3 N.A. 53.3 20 40 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 8 0 8 0 15 29 22 8 15 22 8 22 8 8 % A
% Cys: 0 0 0 0 8 0 0 0 8 0 8 0 8 0 0 % C
% Asp: 0 0 0 8 0 8 0 8 0 0 15 15 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 0 0 8 8 8 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 36 8 8 8 15 0 8 8 15 0 22 0 0 % G
% His: 0 0 0 0 0 0 0 0 22 0 0 0 0 0 0 % H
% Ile: 22 29 0 8 0 0 0 0 0 8 0 0 8 0 0 % I
% Lys: 0 8 15 8 8 0 8 15 22 0 0 8 8 15 22 % K
% Leu: 0 0 0 0 0 8 8 0 15 0 0 8 0 8 0 % L
% Met: 8 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 15 0 0 0 0 0 % N
% Pro: 0 8 8 15 0 0 0 8 8 0 0 0 0 0 8 % P
% Gln: 8 0 0 8 15 8 8 0 0 0 8 29 0 0 0 % Q
% Arg: 0 8 8 0 22 0 0 8 0 15 0 8 0 15 15 % R
% Ser: 15 8 8 36 36 36 15 29 8 8 22 15 22 15 36 % S
% Thr: 8 22 8 0 8 0 15 8 8 29 8 8 0 36 8 % T
% Val: 8 15 8 0 0 15 8 0 0 0 0 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _